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Head and neck cancer cells and xenografts are very sensitive to palytoxin: decrease of c-jun n-terminale kinase-3 expression enhances palytoxin toxicity

OBJECTIVES: Palytoxin (PTX), a marine toxin isolated from the Cnidaria (zooanthid) Palythoa caribaeorum is one of the most potent non-protein substances known. It is a very complex molecule that presents both lipophilic and hydrophilic areas. The effect of PTX was investigated in a series of experim...

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Bibliografiske detaljer
Main Authors: Görögh, Tibor, Bèress, László, Quabius, Elgar S, Ambrosch, Petra, Hoffmann, Markus
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585753/
https://ncbi.nlm.nih.gov/pubmed/23409748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-12
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