Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts

In mice and humans, it has been shown that embryonic and adult fibroblasts can be reprogrammed into pluripotency by introducing 4 transcription factors, Oct3/4, Klf4, Sox2, and c-Myc (OKSM). Here, we report the derivation of induced pluripotent stem cells (iPSCs) from adult canine fibroblasts by ret...

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Detalhes bibliográficos
Main Authors: Koh, Sehwon, Thomas, Rachael, Tsai, Shengdar, Bischoff, Steve, Lim, Ji-Hey, Breen, Matthew, Olby, Natasha J., Piedrahita, Jorge A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585736/
https://ncbi.nlm.nih.gov/pubmed/23016947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0393
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