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Exploring the Contribution of Estrogen to Amyloid-Beta Regulation: A Novel Multifactorial Computational Modeling Approach
According to the amyloid hypothesis, Alzheimer Disease results from the accumulation beyond normative levels of the peptide amyloid-β (Aβ). Perhaps because of its pathological potential, Aβ and the enzymes that produce it are heavily regulated by the molecular interactions occurring within cells, in...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585711/ https://ncbi.nlm.nih.gov/pubmed/23459573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00016 |
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