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Mutations in an essential U2 small nuclear RNA structure cause cold-sensitive U2 small nuclear ribonucleoprotein function by favoring competing alternative U2 RNA structures.

Mutations in stem-loop IIa of yeast U2 RNA cause cold-sensitive growth and cold-sensitive U2 small nuclear ribonucleoprotein function in vitro. Cold-sensitive U2 small nuclear RNA adopts an alternative conformation that occludes the loop and disrupts the stem but does so at both restrictive and perm...

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Bibliografiska uppgifter
Huvudupphovsmän: Zavanelli, M I, Britton, J S, Igel, A H, Ares, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC358527/
https://ncbi.nlm.nih.gov/pubmed/8114704
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