The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements.

Lignende værker

• Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.
  af: Wegenka, U M, et al.
  Udgivet: (1993)
• The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.
  af: Wegenka, U M, et al.
  Udgivet: (1994)
• A factor induced by differentiation signals in cells of the macrophage lineage binds to the gamma interferon activation site.
  af: Eilers, A, et al.
  Udgivet: (1994)
• The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.
  af: Kanno, Y, et al.
  Udgivet: (1993)
• Roles of interferon-gamma and interleukin-4 in murine lupus.
  af: Peng, S L, et al.
  Udgivet: (1997)