In Type 1 Diabetes a Subset of Anti-Coxsackievirus B4 Antibodies Recognize Autoantigens and Induce Apoptosis of Pancreatic Beta Cells

Type 1 diabetes is characterized by autoimmune destruction of pancreatic beta cells. The role played by autoantibodies directed against beta cells antigens in the pathogenesis of the disease is still unclear. Coxsackievirus B infection has been linked to the onset of type 1 diabetes; however its pre...

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Detalhes bibliográficos
Principais autores: Bason, Caterina, Lorini, Renata, Lunardi, Claudio, Dolcino, Marzia, Giannattasio, Alessandro, d’Annunzio, Giuseppe, Rigo, Antonella, Pedemonte, Nicoletta, Corrocher, Roberto, Puccetti, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585221/
https://ncbi.nlm.nih.gov/pubmed/23469060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057729
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