Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to be complex, is poorly understood. Here we report the largest ever genome-wide association study (45,771 participants) on myopia in Europeans....

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Главные авторы: Kiefer, Amy K., Tung, Joyce Y., Do, Chuong B., Hinds, David A., Mountain, Joanna L., Francke, Uta, Eriksson, Nicholas
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585144/
https://ncbi.nlm.nih.gov/pubmed/23468642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003299
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