The Apoptogenic Toxin AIP56 Is a Metalloprotease A-B Toxin that Cleaves NF-κb P65

AIP56 (apoptosis-inducing protein of 56 kDa) is a major virulence factor of Photobacterium damselae piscicida (Phdp), a Gram-negative pathogen that causes septicemic infections, which are among the most threatening diseases in mariculture. The toxin triggers apoptosis of host macrophages and neutrop...

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Autori principali: Silva, Daniela S., Pereira, Liliana M. G., Moreira, Ana R., Ferreira-da-Silva, Frederico, Brito, Rui M., Faria, Tiago Q., Zornetta, Irene, Montecucco, Cesare, Oliveira, Pedro, Azevedo, Jorge E., Pereira, Pedro J. B., Macedo-Ribeiro, Sandra, do Vale, Ana, dos Santos, Nuno M. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585134/
https://ncbi.nlm.nih.gov/pubmed/23468618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003128
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