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Deletion of Vacuolar Proton-translocating ATPase V(o)a Isoforms Clarifies the Role of Vacuolar pH as a Determinant of Virulence-associated Traits in Candida albicans
Vacuolar proton-translocating ATPase (V-ATPase) is a central regulator of cellular pH homeostasis, and inactivation of all V-ATPase function has been shown to prevent infectivity in Candida albicans. V-ATPase subunit a of the V(o) domain (V(o)a) is present as two fungal isoforms: Stv1p (Golgi) and V...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585055/ https://ncbi.nlm.nih.gov/pubmed/23316054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426197 |
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