Comparison of Visceral Leishmaniasis Diagnostic Antigens in African and Asian Leishmania donovani Reveals Extensive Diversity and Region-specific Polymorphisms

BACKGROUND: Visceral leishmaniasis (VL), caused by infection with Leishmania donovani complex, remains a major public health problem in endemic regions of South Asia, East Africa, and Brazil. If untreated, symptomatic VL is usually fatal. Rapid field diagnosis relies principally on demonstration of...

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Main Authors: Bhattacharyya, Tapan, Boelaert, Marleen, Miles, Michael A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585016/
https://ncbi.nlm.nih.gov/pubmed/23469296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002057
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