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Neopterin Is a Cerebrospinal Fluid Marker for Treatment Outcome Evaluation in Patients Affected by Trypanosoma brucei gambiense Sleeping Sickness

BACKGROUND: Post-therapeutic follow-up is essential to confirm cure and to detect early treatment failures in patients affected by sleeping sickness (HAT). Current methods, based on finding of parasites in blood and cerebrospinal fluid (CSF) and counting of white blood cells (WBC) in CSF, are imperf...

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Bibliographische Detailangaben
Hauptverfasser: Tiberti, Natalia, Lejon, Veerle, Hainard, Alexandre, Courtioux, Bertrand, Robin, Xavier, Turck, Natacha, Kristensson, Krister, Matovu, Enock, Enyaru, John Charles, Mumba Ngoyi, Dieudonné, Krishna, Sanjeev, Bisser, Sylvie, Ndung′u, Joseph Mathu, Büscher, Philippe, Sanchez, Jean-Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585011/
https://ncbi.nlm.nih.gov/pubmed/23469311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002088
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