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Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export.

Eukaryotic proteins initially synthesized with a C-terminal CAAX motif (C is Cys, A is aliphatic, and X can be one of several amino acids) undergo a series of modifications involving isoprenylation of the Cys residue, proteolysis of AAX, and alpha-carboxyl methyl esterification of the newly formed i...

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Publicat a:Mol Cell Biol
Autors principals: Sapperstein, S, Berkower, C, Michaelis, S
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.2.1438-1449.1994
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