The B Subunit of an AB5 Toxin Produced by Salmonella enterica Serovar Typhi Up-Regulates Chemokines, Cytokines, and Adhesion Molecules in Human Macrophage, Colonic Epithelial, and Brain Microvascular Endothelial Cell Lines

The principal function of bacterial AB5 toxin B subunits is to interact with glycan receptors on the surfaces of target cells and mediate the internalization of holotoxin. However, B subunit-receptor interactions also have the potential to impact cell signaling pathways and, in so doing, contribute...

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Main Authors: Wang, Hui, Paton, James C., Herdman, Brock P., Rogers, Trisha J., Beddoe, Travis, Paton, Adrienne W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584882/
https://ncbi.nlm.nih.gov/pubmed/23250951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01043-12
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