The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex.

Binding of the mammalian transcription factor E2F to the adenovirus E2a early promoter is modulated through interaction with the viral E4-6/7 protein. E4-6/7 induces the cooperative and stable binding of E2F in vitro to two correctly spaced and inverted E2F binding sites in the E2a promoter (E2F ind...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Obert, S, O'Connor, R J, Schmid, S, Hearing, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.2.1333-1346.1994
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