Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice

BACKGROUND & AIMS: Little is known about factors that regulate intestinal epithelial differentiation; microbial recognition receptors such as Toll-like receptor (TLR)4 might be involved. We investigated whether intestinal TLR4 regulates epithelial differentiation and is involved in development o...

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Detalhes bibliográficos
Main Authors: Sodhi, Chhinder P., Neal, Matthew D., Siggers, Richard, Sho, Shonan, Ma, Congrong, Branca, Maria F., Prindle, Thomas, Russo, Anthony M., Afrazi, Amin, Good, Misty, Brower–Sinning, Rachel, Firek, Brian, Morowitz, Michael J., Ozolek, John A., Gittes, George K., Billiar, Timothy R., Hackam, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584415/
https://ncbi.nlm.nih.gov/pubmed/22796522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.05.053
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