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MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase 3.

The yeast gene MCK1 encodes a serine/threonine protein kinase that is thought to function in regulating kinetochore activity and entry into meiosis. Disruption of MCK1 confers a cold-sensitive phenotype, a temperature-sensitive phenotype, and sensitivity to the microtubule-destabilizing drug benomyl...

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Bibliographic Details
Main Authors: Puziss, J W, Hardy, T A, Johnson, R B, Roach, P J, Hieter, P
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC358431/
https://ncbi.nlm.nih.gov/pubmed/8264650
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