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A mutation in the second largest subunit of TFIIIC increases a rate-limiting step in transcription by RNA polymerase III.

In previous studies, we have shown that the PCF1-1 mutation of Saccharomyces cerevisiae suppresses the negative effect of a tRNA gene A block promoter mutation in vivo and increases the transcription of a variety of RNA polymerase III genes in vitro. Here, we report that PCF1 encodes the second larg...

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Main Authors: Rameau, G, Puglia, K, Crowe, A, Sethy, I, Willis, I
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC358430/
https://ncbi.nlm.nih.gov/pubmed/8264649
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