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Modeling prostate cancer in mice: Something old, something new, something premalignant, something metastatic

More than 15 years ago the first generation of genetically-engineered mouse (GEM) models of prostate cancer was introduced. These transgenic models utilized prostate-specific promoters to express SV40 oncogenes specifically in prostate epithelium. Since the description of these initial models, there...

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Detalhes bibliográficos
Main Authors: Irshad, Shazia, Abate-Shen, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584242/
https://ncbi.nlm.nih.gov/pubmed/23114843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-012-9409-1
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