Cell-free production of integral membrane aspartic acid proteases reveals zinc-dependent methyltransferase activity of the Pseudomonas aeruginosa prepilin peptidase PilD

Integral membrane aspartic acid proteases are receiving growing recognition for their fundamental roles in cellular physiology of eukaryotes and prokaryotes, and may be medically important pharmaceutical targets. The Gram-negative Pseudomonas aeruginosa PilD and the archaeal Methanococcus voltae Fla...

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Bibliographic Details
Main Authors: Aly, Khaled A, Beebe, Emily T, Chan, Chi H, Goren, Michael A, Sepúlveda, Carolina, Makino, Shin-ichi, Fox, Brian G, Forest, Katrina T
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584216/
https://ncbi.nlm.nih.gov/pubmed/23255525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.51
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