NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype.

In order to determine whether chronic elevation of intracellular diacylglycerol levels generated by hydrolysis of phosphatidylcholine (PC) by PC-hydrolyzing phospholipase C (PC-PLC) is oncogenic, we generated stable transfectants of NIH 3T3 cells expressing the gene encoding PC-PLC from Bacillus cer...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Johansen, T, Bjørkøy, G, Overvatn, A, Diaz-Meco, M T, Traavik, T, Moscat, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.646-654.1994
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