The C-protein tetramer binds 230 to 240 nucleotides of pre-mRNA and nucleates the assembly of 40S heterogeneous nuclear ribonucleoprotein particles.

A series of in vitro protein-RNA binding studies using purified native (C1)3C2 and (A2)3B1 tetramers, total soluble heterogeneous nuclear ribonucleoprotein (hnRNP), and pre-mRNA molecules differing in length and sequence have revealed that a single C-protein tetramer has an RNA site size of 230 to 2...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Huang, M, Rech, J E, Northington, S J, Flicker, P F, Mayeda, A, Krainer, A R, LeStourgeon, W M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358402/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264621/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.518
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