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Meiotic Sex Chromosome Inactivation Is Disrupted in Sterile Hybrid Male House Mice

In male mammals, the X and Y chromosomes are transcriptionally silenced in primary spermatocytes by meiotic sex chromosome inactivation (MSCI) and remain repressed for the duration of spermatogenesis. Here, we test the longstanding hypothesis that disrupted MSCI might contribute to the preferential...

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Библиографические подробности
Главные авторы: Campbell, Polly, Good, Jeffrey M., Nachman, Michael W.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584000/
https://ncbi.nlm.nih.gov/pubmed/23307891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.148635
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