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Meiotic Sex Chromosome Inactivation Is Disrupted in Sterile Hybrid Male House Mice
In male mammals, the X and Y chromosomes are transcriptionally silenced in primary spermatocytes by meiotic sex chromosome inactivation (MSCI) and remain repressed for the duration of spermatogenesis. Here, we test the longstanding hypothesis that disrupted MSCI might contribute to the preferential...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584000/ https://ncbi.nlm.nih.gov/pubmed/23307891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.148635 |
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