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In situ conversion of tumors into autologous tumor-associated antigen vaccines by intratumoral injection of α-gal glycolipids
The immunogenicity of autologous tumor-associated antigens (TAAs) is markedly increased upon the intratumoral injection of α-gal glycolipids, which insert into tumor cell membranes. The binding of natural anti-Gal antibodies to these glycolipids activates the complement system and recruits antigen-p...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2013
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583920/ https://ncbi.nlm.nih.gov/pubmed/23483105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22449 |
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