Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs

MicroRNAs (miRNAs) are important players of post-transcriptional gene regulation. Individual miRNAs can target multiple mRNAs and a single mRNA can be targeted by many miRNAs. We hypothesized that miRNAs select and regulate their targets based on their own expression levels, those of their target mR...

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Autors principals: Shu, Jingmin, Xia, Zhilian, Li, Lihua, Liang, Ellen T., Slipek, Nicholas, Shen, Dawen, Foo, Jasmine, Subramanian, Subbaya, Steer, Clifford J.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583858/
https://ncbi.nlm.nih.gov/pubmed/22995834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21998
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