Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells.

Retinoid X receptors (RXRs) heterodimerize with multiple nuclear hormone receptors and are thought to exert pleiotropic functions. To address the role of RXRs in retinoic acid- (RA) mediated gene regulation, we designed a dominant negative RXR beta. This mutated receptor, termed DBD-, lacked the DNA...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Minucci, S, Zand, D J, Dey, A, Marks, M S, Nagata, T, Grippo, J F, Ozato, K
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.360-372.1994
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