Cytochrome P450 2E1 Gene Polymorphisms/Haplotypes and Anti-Tuberculosis Drug-Induced Hepatitis in a Chinese Cohort

OBJECTIVE: The pathogenic mechanism of anti-tuberculosis (anti-TB) drug-induced hepatitis is associated with drug metabolizing enzymes. No tagging single-nucleotide polymorphisms (tSNPs) of cytochrome P450 2E1(CYP2E1) in the risk of anti-TB drug-induced hepatitis have been reported. The present stud...

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Главные авторы: Tang, Shaowen, Lv, Xiaozhen, Zhang, Yuan, Wu, Shanshan, Yang, Zhirong, Xia, Yinyin, Tu, Dehua, Deng, Peiyuan, Ma, Yu, Chen, Dafang, Zhan, Siyan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583841/
https://ncbi.nlm.nih.gov/pubmed/23460870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057526
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