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Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.

NF-IL6 and AP-1 family transcription factors are coordinately induced by interleukin-6 (IL-6) in a cell-type-specific manner, suggesting that they mediate IL-6 signals in the nucleus. We show that the basic leucine zipper (bZIP) region of NF-IL6 mediates a direct association with the bZIP regions of...

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Publicat a:Mol Cell Biol
Autors principals: Hsu, W, Kerppola, T K, Chen, P L, Curran, T, Chen-Kiang, S
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.268-276.1994
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