Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma

Epidermal growth factor receptor (EGFR) is commonly overexpressed in malignant pleural mesothelioma (MPM). Cetuximab is a chimeric mouse-human antibody targeted against EGFR and induces potent antibody-dependent cellular cytotoxicity (ADCC). The action of cetuximab against MPM cells has not been wel...

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Autores principales: KURAI, JUN, CHIKUMI, HIROKI, HASHIMOTO, KIYOSHI, TAKATA, MIYAKO, SAKO, TAKANORI, YAMAGUCHI, KOSUKE, KINOSHITA, NAOKI, WATANABE, MASANARI, TOUGE, HIROKAZU, MAKINO, HARUHIKO, IGISHI, TADASHI, HAMADA, HIRONOBU, YANO, SEIJI, SHIMIZU, EIJI
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583649/
https://ncbi.nlm.nih.gov/pubmed/22922885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1607
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