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γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products

Taxanes, including docetaxel, are widely used for the treatment of squamous cell carcinoma of the head and neck. However, the gastrointestinal toxicity of docetaxel has limited its high-dose clinical use. In this study, we examined the synergistic anticancer effects of combined low-dose docetaxel an...

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Bibliografski detalji
Glavni autori: KANI, KOUICHI, MOMOTA, YUKIHIRO, HARADA, MICHITO, YAMAMURA, YOSHIKO, AOTA, KEIKO, YAMANOI, TOMOKO, TAKANO, HIDEYUKI, MOTEGI, KATSUMI, AZUMA, MASAYUKI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583629/
https://ncbi.nlm.nih.gov/pubmed/23138939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1692
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