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Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma
MicroRNAs (miRNAs) are small non-coding RNAs that function as endogenous silencers of target genes. Some tumor-suppressive miRNAs are known to be epigenetically silenced by promoter DNA methylation in cancer. In the present study, we aimed to identify miRNA genes that are silenced by DNA hypermethyl...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583616/ https://ncbi.nlm.nih.gov/pubmed/23229728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1724 |
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