Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum

We examined the effects of the preferential cyclooxygenase-2 (COX-2) inhibitor celecoxib on tumorigenesis, angiogenesis, apoptosis, vascular endothelial growth factor (VEGF) protein expression and metastasis in HT-29 human colorectal carcinoma cell xenografts in nude mouse rectum. COX-2 mRNA express...

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Main Authors: NINOMIYA, ITASU, NAGAI, NOBORU, OYAMA, KATSUNOBU, HAYASHI, HIRONORI, TAJIMA, HIDEHIRO, KITAGAWA, HIROHISA, FUSHIDA, SACHIO, FUJIMURA, TAKASHI, OHTA, TETSUO
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2012
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583608/
https://ncbi.nlm.nih.gov/pubmed/22751903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1885
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