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The Antinociceptive Effect of Milnacipran in the Monosodium Iodoacetate Model of Osteoarthritis Pain and Its Relation to Changes in Descending Inhibition

Osteoarthritis (OA) is a chronic joint disorder whose principal symptom is chronic pain. Current analgesics are inadequate and the mechanisms contributing to this pain are poorly understood but likely to include both local joint changes and central consequences. These studies used monoamine receptor...

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Detalhes bibliográficos
Main Authors: Burnham, Liam J., Dickenson, Anthony H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583501/
https://ncbi.nlm.nih.gov/pubmed/23297162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199489
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