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Molecular and genomic approach for understanding the gene-environment interaction between Nrf2 deficiency and carcinogenic nickel-induced DNA damage

Nickel (II) is a toxic and carcinogenic metal which induces a redox imbalance following oxidative stress. Nuclear factor erythroid-2 related factor 2 (Nrf2) is a redox factor that regulates oxidation/reduction status and consequently mediates cytoprotective responses against exposure to environmenta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KIM, HYE LIM, SEO, YOUNG ROK
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583472/
https://ncbi.nlm.nih.gov/pubmed/23023193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.2057
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