Novel HER2 Aptamer Selectively Delivers Cytotoxic Drug to HER2-positive Breast Cancer Cells in Vitro

BACKGROUND: Aptamer-based tumor targeted drug delivery system is a promising approach that may increase the efficacy of chemotherapy and reduce the related toxicity. HER2 protein is an attractive target for tumor-specific drug delivery because of its overexpression in multiple malignancies, includin...

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Autori principali: Liu, Zhe, Duan, Jin-Hong, Song, Yong-Mei, Ma, Jie, Wang, Feng-Dan, Lu, Xin, Yang, Xian-Da
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583217/
https://ncbi.nlm.nih.gov/pubmed/22817844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-148
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