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Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments
BACKGROUND: Treatment of solid tumors with vascular disrupting agent OXi4503 results in over 90% tumor destruction. However, a thin rim of viable cells persists in the tumor periphery following treatment, contributing to subsequent recurrence. This study investigates inherent differences in the micr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583184/ https://ncbi.nlm.nih.gov/pubmed/23153292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-522 |
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