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Total Synthesis of Sedum Alkaloids via Catalyst Controlled aza-Cope Rearrangement and Hydroformylation with Formaldehyde

[Image: see text] The catalytic asymmetric aminoallylation of chiral aldehydes is developed as a new method for the catalyst controlled synthesis of syn- and anti-1,3-aminoalcohols. This methodology is highlighted in the synthesis of the sedum alkaloids (+)-sedridine and (+)-allosedridine both of wh...

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Detalhes bibliográficos
Main Authors: Ren, Hong, Wulff, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582941/
https://ncbi.nlm.nih.gov/pubmed/23259754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302769r
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