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Transient acidification and subsequent proinflammatory cytokine stimulation of astrocytes induce distinct activation phenotypes

The foot processes of astrocytes cover over 60% of the surface of brain microvascular endothelial cells, regulating tight junction integrity. Retraction of astrocyte foot processes has been postulated to be a key mechanism in pathology. Therefore, movement of an astrocyte in response to a proinflamm...

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Autors principals: Renner, Nicole A., Sansing, Hope A., Inglis, Fiona M., Mehra, Smriti, Kaushal, Deepak, Lackner, Andrew A., MacLean, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582839/
https://ncbi.nlm.nih.gov/pubmed/23154943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24283
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