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Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex

BACKGROUND: The 5-hydroxytryptamine 2A receptor, encoded by HTR2A, is a major post-synaptic target for serotonin in the human brain and a therapeutic drug target. Despite hundreds of genetic associations investigating HTR2A polymorphisms in neuropsychiatric disorders and therapies, the role of genet...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, Ryan M., Papp, Audrey C., Webb, Amy, Ruble, Cara L., Munsie, Leanne M., Nisenbaum, Laura K., Kleinman, Joel E., Lipska, Barbara K., Sadee, Wolfgang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582836/
https://ncbi.nlm.nih.gov/pubmed/23158458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.09.028
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