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A Core Chromatin Remodeling Factor Instructs Global Chromatin Signaling Through Multivalent Reading of Nucleosome Codes
ATP-dependent NuRD repressor complexes involve combinatorial assembly of its subunits. However, the mechanism of gene transcription by MTA1/NuRD remains enigmatic. Here we report that MTA1 methylation by G9a methytransferase and demethylation by LSD1 determines the nucleosome remodeling and transcri...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582764/ https://ncbi.nlm.nih.gov/pubmed/23352453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.016 |
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