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Blood-Brain Barrier Breakdown after Embolic Stroke in Rats Occurs without Ultrastructural Evidence for Disrupting Tight Junctions

The term blood-brain barrier (BBB) relates to the ability of cerebral vessels to hold back hydrophilic and large molecules from entering the brain, thereby crucially contributing to brain homeostasis. In fact, experimental opening of endothelial tight junctions causes a breakdown of the BBB evidence...

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Detalhes bibliográficos
Main Authors: Krueger, Martin, Härtig, Wolfgang, Reichenbach, Andreas, Bechmann, Ingo, Michalski, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582567/
https://ncbi.nlm.nih.gov/pubmed/23468865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056419
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