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Carprofen for perioperative analgesia causes early anastomotic leakage in the rat ileum

BACKGROUND: There is increasing evidence that perioperative use of NSAIDs may compromise the integrity of intestinal anastomoses. This study aims to characterize the negative effects of carprofen on early anastomotic healing in the rat ileum. RESULTS: In 159 male Wistar rats an anastomosis was const...

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Bibliografiske detaljer
Main Authors: van der Vijver, Rozemarijn J, van Laarhoven, Cees JHM, Lomme, Roger MLM, Hendriks, Thijs
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582476/
https://ncbi.nlm.nih.gov/pubmed/23270317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-8-247
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