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Three-Dimensional Architecture of the Rod Sensory Cilium and its Disruption in Retinal Neurodegeneration
Defects in primary cilia lead to devastating disease due to their roles in sensation and developmental signaling, but much is unknown about ciliary structure and mechanisms of their formation and maintenance. We used cryo-electron tomography to obtain three-dimensional maps of the connecting cilium...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582337/ https://ncbi.nlm.nih.gov/pubmed/23178122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.038 |
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