Three-Dimensional Architecture of the Rod Sensory Cilium and its Disruption in Retinal Neurodegeneration

Defects in primary cilia lead to devastating disease due to their roles in sensation and developmental signaling, but much is unknown about ciliary structure and mechanisms of their formation and maintenance. We used cryo-electron tomography to obtain three-dimensional maps of the connecting cilium...

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Detaylı Bibliyografya
Asıl Yazarlar: Gilliam, Jared C., Chang, Juan T., Sandoval, Ivette M., Zhang, Youwen, Li, Tiansen, Pittler, Steven J., Chiu, Wah, Wensel, Theodore G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582337/
https://ncbi.nlm.nih.gov/pubmed/23178122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.038
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