Enhanced Antitumor Activity of the Photosensitizer meso-Tetra(N-methyl-4-pyridyl) Porphine Tetra Tosylate through Encapsulation in Antibody-Targeted Chitosan/Alginate Nanoparticles

[Image: see text] meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate (TMP) is a photosensitizer that can be used in photodynamic therapy (PDT) to induce cell death through generation of reactive oxygen species in targeted tumor cells. However, TMP is highly hydrophilic, and therefore, its abilit...

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Hlavní autoři: Abdelghany, Sharif M., Schmid, Daniela, Deacon, Jill, Jaworski, Jakub, Fay, Francois, McLaughlin, Kirsty M., Gormley, Julie A., Burrows, James F., Longley, Daniel B., Donnelly, Ryan F., Scott, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2013
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582313/
https://ncbi.nlm.nih.gov/pubmed/23327610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301858a
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