Deletion of von Hippel–Lindau Protein Converts Renin-Producing Cells into Erythropoietin-Producing Cells

States of low perfusion pressure of the kidney associate with hyperplasia or expansion of renin-producing cells, but it is unknown whether hypoxia-triggered genes contribute to these changes. Here, we stabilized hypoxia-inducible transcription factors (HIFs) in mice by conditionally deleting their n...

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Hlavní autoři: Kurt, Birguel, Paliege, Alexander, Willam, Carsten, Schwarzensteiner, Ilona, Schucht, Kathrin, Neymeyer, Hanna, Sequeira-Lopez, Maria Luisa S., Bachmann, Sebastian, Gomez, R. Ariel, Eckardt, Kai-Uwe, Kurtz, Armin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2013
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582205/
https://ncbi.nlm.nih.gov/pubmed/23393316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012080791
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