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Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics

Mitochondrial dysfunction is associated with a broad range of pathologies including diabetes, ethanol toxicity, metabolic syndrome, and cardiac failure. It is now becoming clear that maintaining mitochondrial quality through a balance between biogenesis, reserve capacity, and mitophagy is critical i...

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Detalhes bibliográficos
Main Authors: Mitchell, Tanecia, Chacko, Balu, Ballinger, Scott, Bailey, Shannon, Zhang, Jianhua, Darley-Usmar, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582193/
https://ncbi.nlm.nih.gov/pubmed/23356271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20120231
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