Natural killer cell mediated pathogenesis determines outcome of central nervous system infection with Venezuelan equine encephalitis virus in C3H/HeN mice

TC83 is a human vaccine with investigational new drug status and is used as a prototype Venezuelan equine encephalitis virus for pathogenesis and antiviral research. Differing from other experimental models, the virus causes high titer infection in the brain and 90–100% mortality in the C3H/HeN muri...

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Bibliographic Details
Main Authors: Taylor, Katherine, Kolokoltsova, Olga, Patterson, Michael, Poussard, Allison, Smith, Jennifer, Estes, D. Mark, Paessler, Slobodan
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582184/
https://ncbi.nlm.nih.gov/pubmed/22525795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.03.076
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