2-photon imaging of phagocyte-mediated T cell activation in the CNS

Autoreactive T cells can infiltrate the CNS to cause disorders such as multiple sclerosis. In order to visualize T cell activation in the CNS, we introduced a truncated fluorescent derivative of nuclear factor of activated T cells (NFAT) as a real-time T cell activation indicator. In experimental au...

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Main Authors: Pesic, Marija, Bartholomäus, Ingo, Kyratsous, Nikolaos I., Heissmeyer, Vigo, Wekerle, Hartmut, Kawakami, Naoto
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2013
主題:
Technical Advance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582148/
https://ncbi.nlm.nih.gov/pubmed/23454769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67233
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