Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia

The formation of clathrin-coated vesicles is essential for intracellular membrane trafficking between subcellular compartments and is triggered by the ARF family of small GTPases. We previously identified SMAP1 as an ARF6 GTPase-activating protein that functions in clathrin-dependent endocytosis. Be...

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Hlavní autoři: Kon, Shunsuke, Minegishi, Naoko, Tanabe, Kenji, Watanabe, Toshio, Funaki, Tomo, Wong, Won Fen, Sakamoto, Daisuke, Higuchi, Yudai, Kiyonari, Hiroshi, Asano, Katsutoshi, Iwakura, Yoichiro, Fukumoto, Manabu, Osato, Motomi, Sanada, Masashi, Ogawa, Seishi, Nakamura, Takuro, Satake, Masanobu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582118/
https://ncbi.nlm.nih.gov/pubmed/23434593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63711
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