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Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance

Chronic consumption of a fat-rich diet leads to attenuation of leptin signaling in hypothalamic neurons, a hallmark feature of cellular leptin resistance. To date, little is known about the temporal and spatial dysregulation of neuronal function under conditions of nutrient excess. We show that agou...

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Xehetasun bibliografikoak
Egile Nagusiak: Olofsson, Louise E., Unger, Elizabeth K., Cheung, Clement C., Xu, Allison W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581908/
https://ncbi.nlm.nih.gov/pubmed/23386726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218284110
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