Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice

Neuregulin 1 (NRG1) is linked to an increased risk of developing schizophrenia and cannabis dependence. Mice that are hypomorphic for Nrg1 (Nrg1 HET mice) display schizophrenia-relevant behavioral phenotypes and aberrant expression of serotonin and glutamate receptors. Nrg1 HET mice also display idi...

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Detalhes bibliográficos
Main Authors: Spencer, Jarrah R., Darbyshire, Keturah M. E., Boucher, Aurelie A., Kashem, Mohammed A., Long, Leonora E., McGregor, Iain S., Karl, Tim, Arnold, Jonathon C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581856/
https://ncbi.nlm.nih.gov/pubmed/23447498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00015
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